Standard thyroid care checks TSH and maybe T4. We test across three interconnected hormonal axes to see the complete picture of what's driving your symptoms.
The master metabolic circuit. Most doctors check TSH alone and call it a day. But TSH can be "normal" while your actual thyroid hormones are sub-optimal. We test the full cascade to understand how your brain signals your thyroid, what your thyroid produces, and how your body converts and uses those hormones.
Brain's signal to the thyroid. High = underactive. But "normal" ranges are wide and miss subclinical issues.
The main hormone your thyroid produces. The raw material that gets converted to the active form.
The active thyroid hormone. This is what actually powers your cells. Low T3 with normal T4 = conversion problem.
The metabolic brake. High rT3 means your body is blocking active T3, often from stress or inflammation.
Markers for autoimmune thyroid disease (Hashimoto's). Can be elevated years before TSH becomes abnormal.
Another autoimmune marker. Together with TPO, gives a complete picture of autoimmune thyroid activity.
Chronic stress doesn't just make you feel tired, it actively suppresses thyroid function. When your adrenals are pumping cortisol, your body increases reverse T3 production, blocking the active hormone. You can't fix the thyroid without addressing the stress response.
Morning cortisol shows your baseline stress response. Both high and low values indicate HPA dysregulation.
An adrenal hormone that balances cortisol. Low DHEA-S with high cortisol = chronic stress pattern.
Critical for immune regulation and thyroid function. Deficiency is common in thyroid patients and worsens symptoms.
Iron is required for thyroid hormone production. Ferritin, serum iron, and TIBC reveal hidden deficiencies.
Your sex hormones and thyroid are in constant dialogue. Estrogen dominance increases thyroid-binding globulin, trapping your thyroid hormones so they can't reach your cells. Low testosterone (in any gender) magnifies fatigue and brain fog. Treating the thyroid without looking at sex hormones misses half the picture.
Primary estrogen. Excess estrogen increases TBG, reducing available thyroid hormone at the cellular level.
Balances estrogen and supports thyroid function. Low progesterone is a hidden driver of thyroid symptoms.
Critical for energy, mood, and muscle. Thyroid dysfunction directly suppresses testosterone production.
Sex hormone-binding globulin. Elevated by thyroid medication, it can trap hormones and cause symptoms despite "good" levels.
TSH can be "normal" while Free T3 is tanked and Reverse T3 is sky-high. You feel terrible, but your labs say you're fine. We don't accept that.
High cortisol suppresses TSH. Low estrogen changes thyroid binding. Each axis affects the others. Testing one in isolation gives you a fraction of the story.
Lab reference ranges cover 95% of the population, including sick people. We use functional ranges that define where you feel your best, not just where you avoid disease.